Lyme Disease Treatment

Antibiotics are used to treat Lyme Disease.

  •  NICE Guidelines for Lyme disease state:
    • "Diagnose and treat Lyme disease without laboratory testing in people with erythema migrans".
    • Adults with an erythema migrans rash should be treated with "oral doxycycline: 100 mg twice per day or 200 mg once per day for 21 days". More details on treatment for other symptoms is given in their Management Recommendations section.
    • "Do not rule out diagnosis if tests are negative but there is high clinical suspicion of Lyme disease".
    • "Consider starting treatment with antibiotics while waiting for the results if there is a high clinical suspicion".
    • "Consider a second course of antibiotics for people with ongoing symptoms if treatment may have failed".
  • The NICE Quality Standard states: "People with Lyme disease have initial antibiotic treatment, with the antibiotic, dosage and duration determined by their symptoms."

A summary of the NICE Guideline treatment section can be found here https://www.nice.org.uk/guidance/ng95/chapter/Recommendations#management 

If not treated promptly and sufficiently, Lyme Disease may become persistent and longer courses of antibiotics may be necessary. Treatment failures have been documented even in the best circumstances.

It is important for treatment to be individualised and carefully monitored. Symptoms that change over time or do not resolve should be reported to the treating physician, who may need to consider other treatment regimes and diagnoses.