Antibiotics are used to treat Lyme Disease. ILADS treatment guidelines recommend 4-6 weeks of doxycycline, amoxicillin, or cefuroxime for cases of early Lyme disease. This should be effective for the majority of people. Treatment may be extended if symptoms remain.
If not treated promptly and sufficiently, Lyme Disease may become persistent and longer courses of antibiotics may be necessary. Treatment failures have been documented even in the best circumstances.
It is important for treatment to be individualised and carefully monitored. Symptoms that change over time or do not resolve should be reported to the treating physician, who may need to consider other treatment regimes and diagnoses.