Perinatal transmission of the agent of human granulocytic ehrlichiosis

Published Date
The New England Journal of Medicine
N Engl J Med . 1998 Aug 6;339(6):375-8
Horowitz HW
Kilchevsky E
Haber S
Aguero-Rosenfeld M
Kranwinkel E
James EK
Wong SJ
Chu F
Liveris D
Schwartz I

Human granulocytic ehrlichiosis was first described in the United States, in the northern Midwest, in 1994.1 Human granulocytic ehrlichiosis is caused by an organism, still referred to as the agent of human granulocytic ehrlichiosis, that is similar to two animal pathogens, Ehrlichia phagocytophila and E. equi. 2-4 Transmission of human granulocytic ehrlichiosis occurs through the bites of ixodes ticks, which are the arthropod vectors for Borrelia burgdorferi and Babesia microti. 5,6 Human granulocytic ehrlichiosis is an acute, febrile, nonspecific illness that may be severe enough to cause hospitalization and even death, particularly in the elderly.1,7,8 We describe a case of human granulocytic ehrlichiosis that developed in a pregnant woman near term and was transmitted perinatally to her infant.